The drug delivery application of Porous metal–organic frameworks (MOFs) have been investigated due to their unique structures which are built of inorganic nodes and organic ligands. In present study, Uio-67-5-FU was successfully prepared by applied for delivery of 5-fluorouracil (5-FU). Using variety of analytical methods including FTIR, FESEM, EDS, and the prepared nanostructure was characterized. Results revealed the placement of the drug in zeolite is well done and also the in vitro loading and releasing studies, for 5-FU was evaluated. In addition, Based on the in vitro cytotoxicity results, Uio-67-5Fu was able to increase cytotoxicity compared to that of 5-Fu on HT-29 cancerous cells indicating the highlighted role of this drug delivery system. .

This study looks at how public perception is impacted by media coverage. It will examine how news is presented by various media outlets and how public opinion is affected by this coverage. The study will look at both the good and bad effects of media bias, including how stories are presented and how much emphasis is placed on certain viewpoints. Data analysis for the study will include quantitative and qualitative techniques. A poll of the general public will also be included to assess how perceptions have been impacted by media coverage. The results of this study will shed light on the framing of news items and their influence on public opinion. Additionally, it will offer suggestions for minimising bias in news coverage and ensuring that news stories are presented more clearly..

The distribution of prime numbers has captivated mathematicians and scholars for centuries, forming a cornerstone of number theory and providing profound insights into the nature of numbers. Prime numbers, defined as natural numbers greater than 1 that have no positive divisors other than 1 and themselves, are the building blocks of arithmetic. Despite their seemingly simple definition, the pattern in which primes appear among natural numbers is intricate and exhibits both regularities and irregularities that have intrigued researchers for generations. Understanding the distribution of primes is not merely an academic exercise; it has practical implications in fields ranging from cryptography to computer science. The challenge lies in the apparent randomness of prime numbers juxtaposed with the underlying order that mathematicians strive to uncover. The quest to comprehend prime distribution has led to the development of significant mathematical theories and conjectures, some of which remain unresolved to this day. This paper explores key aspects of prime distribution, including the Prime Number Theorem, the Twin Prime Conjecture, prime gaps, digit patterns such as Benford’s Law, the Riemann Hypothesis, and the practical applications of primes in cryptography. Through these discussions, we highlight the profound theoretical and practical implications of prime number distribution..

In recent years, Indian universities have increasingly integrated skill-based courses into their curricula to bridge the gap between academic learning and industry requirements. This shift aims to enhance employability among graduates by equipping them with practical skills relevant to the current job market. This paper explores the integration of skill courses in higher education across various Indian universities, examining their impact on student outcomes, employability, and industry partnerships. The study utilizes a mixed-methods approach, including surveys and interviews with students, faculty, and industry experts, to evaluate the effectiveness of these courses. Results indicate that skill courses significantly improve students' readiness for the workforce, foster innovation, and encourage entrepreneurial initiatives. However, challenges such as resource allocation, faculty training, and curriculum design remain prevalent. The findings underscore the importance of continuous collaboration between academic institutions and industry stakeholders to refine and adapt skill-based education, ensuring alignment with evolving market demands. This paper contributes to the discourse on educational reform in India, highlighting the need for a dynamic approach to integrating skill development in higher education..

The transformative impact of EdTech is revolutionizing education by enhancing accessibility, engagement, and personalization. Through innovative tools and platforms, EdTech startups are dismantling geographical and socio-economic barriers, providing learners from diverse backgrounds with access to high-quality educational resources. These technologies support interactive and adaptive learning, tailoring content to individual needs and leveraging data analytics, artificial intelligence, and immersive technologies like virtual and augmented reality. However, in Jharkhand, the reach and effectiveness of EdTech face significant challenges due to socio-economic disparities, infrastructural limitations, and varied digital literacy levels. Limited internet connectivity, inadequate digital devices, and economic barriers impede the deployment of these solutions. In contrast, more advanced regions benefit from robust infrastructure, widespread digital literacy, and higher economic investment, facilitating seamless EdTech integration. Evaluating the impact of EdTech in Jharkhand reveals both the potential benefits and constraints of these technologies, highlighting the need for solutions tailored to local contexts. Opportunities exist to develop adaptable tools and explore alternative delivery methods to overcome connectivity issues and enhance the effectiveness of EdTech solutions in less developed areas..